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Table 1 Descriptive characteristics of the Health and Retirement Study participants (N = 3,813)

From: Epigenetic age acceleration is associated with blood lipid levels in a multi-ancestry sample of older U.S. adults

Characteristic

Mean (SD) or N (%)

Minimum

Maximum

Age (years)

70.0 (9.3)

56

100

Female sex

2201 (57.7%)

  

Race/ethnicity (self-reported)

   

Non-Hispanic White

2564 (67.2%)

  

Non-Hispanic Black

623 (16.3%)

  

Hispanic

509 (13.3%)

  

All other groups

117 (3.1%)

  

Educational attainment

   

Less than high school degree

633 (16.6%)

  

High school degree or equivalent

2254 (59.1%)

  

College degree and above

926 (24.3%)

  

BMI (kg/m2)

28.9 (6.3)

14.1

70.7

Smoking status

   

Never smoker

1685 (44.2%)

  

Former smoker

1704 (44.7%)

  

Current smoker

424 (11.1%)

  

Lipid-lowering medication use

1869 (49.0%)

  

Fasting at time of blood draw

2531 (66.4%)

  

Blood lipids

  

Total cholesterol (mg/dL) (n = 3,811)

187.6 (41.6)

79.0

355

HDL-C (mg/dL)a

57.0 (18.8)

20.0

159

LDL-C (mg/dL) (n = 3,731)

101.7 (35.0)

11.0

239

Triglycerides (mg/dL) (n = 3,806)a

144.8 (84.0)

33.0

884

Epigenetic age acceleration

   

HorvathAA (years)

0.017 (6.3)

-25.8

25.9

HannumAA (years)

-0.018 (5.1)

-20.9

20.9

PhenoAA (years)

-0.036 (6.8)

-27.3

27.3

GrimAA (years)

0.009 (4.7)

-17.0

18.9

DunedinPACE

1.038 (0.1)

-32.4

55.0

  1. SD, standard deviation; TC, total cholesterol; HDL-C, high-density lipoprotein; LDL-C, low-density lipoprotein; TG, triglycerides; HorvathAA, HorvathAge acceleration; HannumAA, HannumAge acceleration; PhenoAA, LevineAge (PhenoAge) acceleration; GrimAA, GrimAge acceleration; BMI, body mass index
  2. aHDL-C and triglycerides were natural-log transformed prior to analysis