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Table 4 Stratified analyses of the rs982873, rs9588884, rs1813389 polymorphisms with depression risk

From: Association between Mir-17-92 gene promoter polymorphisms and depression in a Chinese population

Variables

Frequency

OR (95% CI)

P value

%

%

rs1813389

   

Depressive episode

Severe

Mild

  

A/A

97 (34.9)

89 (32.1)

1.00 (Ref)

A/G-G/G

181 (65.1)

188 (67.9)

0.88 (0.62–1.26)

0.500

Suicide attempt

Yes

No

  

A/A

79 (32.8)

107 (34.1)

1.00 (Ref)

A/G-G/G

162 (67.2)

207 (65.9)

0.95 (0.65–1.37)

0.770

First-episode patient

Yes

No

  

A/A

91 (32.9)

95 (34.3)

1.00 (Ref)

A/G-G/G

186 (67.2)

182 (65.7)

1.09 (0.76–1.56)

0.650

Family history

Yes

No

  

A/A

25 (25.8)

161 (35.1)

1.00 (Ref)

0.056

A/G-G/G

72 (74.2)

297 (64.8)

1.60 (0.98–2.64)

 

rs9588884

   

Depressive episode

Severe

Mild

  

C/C

93 (33.5)

86 (31.1)

1.00 (Ref)

C/G-G/G

185 (66.5)

191 (69.0)

0.88 (0.62–1.27)

0.500

Suicide attempt

Yes

No

  

C/C

103 (32.8)

76 (31.5)

1.00 (Ref)

C/G-G/G

211 (67.2)

165 (68.5)

0.92 (0.63–1.34)

0.660

First-episode patient

Yes

No

  

C/C

87 (31.7)

92 (33.2)

1.00 (Ref)

C/G-G/G

190 (68.6)

185 (66.8)

1.08 (0.75–1.56)

0.660

Family history

Yes

No

  

C/C

24 (24.7)

155 (33.8)

1.00 (Ref)

0.070

C/G-G/G

73 (75.3)

303 (66.2)

0.63 (0.38–1.05)

 

rs982873

   

Depressive episode

Severe

Mild

  

T/T

94 (33.8)

86 (31.1)

1.00 (Ref)

T/C-C/C

184 (66.2)

191 (69)

0.88 (0.61–1.26)

0.470

Suicide attempt

Yes

No

  

T/T

105 (33.4)

75 (31.1)

1.00 (Ref)

T/C-C/C

209 (66.6)

166 (68.9)

1.13 (0.78–1.65)

0.520

First-episode patient

Yes

No

  

T/T

87 (31.4)

93 (33.6)

1.00 (Ref)

T/C-C/C

190 (68.6)

184 (66.4)

1.11 (0.77–1.60)

0.560

Family history

Yes

No

  

T/T

24 (24.7)

156 (34.1)

1.00 (Ref)

0.060

T/C-C/C

73 (75.3)

302 (65.9)

0.62 (0.38–1.03)

 
  1. CI Confidence interval, OR Odds ratio, OR was adjusted by age and gender