Fig. 3

The weighted correlation network analysis of the differentially expressed genes (DEGs). Selection of the optimal soft-thresholding power for the scale-free network and mean connectivity (A, B). Dendrogram of 3305 DEGs depending on the dissimilarity measure(1-TOM). Each branch represents a gene, and each color represents a co-expression module (C). The number of module genes in the seven modules (D). Correlation analysis of the module eigengenes and immune infiltration score by the EPIC algorithm. Spearson’s correlation coefficient and the corresponding p-value are shown (E). Scatter plots between the gene significance for CAFs and module membership in the green-yellow module (F)