Fig. 1

Manhattan Plots and Q-Q Plots for T2D BMI-unadjusted and BMI-adjusted Models. Manhattan plot (A, C) and Q-Q plot (B, D) for BMI-adjusted (A, B) and for BMI-unadjusted (C, D) GWAS. Manhattan plots represent SNPs (dots) plotted on x-axis in accordance with chromosome position against their corresponding -log10(P). The red horizontal line represents the threshold for genome-wide significance (P < 5 × 10− 08). Q-Q plots represent the quantile distribution of observed P values versus the quantile distribution of expected P values for all SNPs