Fig. 2

The integration of AP datasets and differential expression analysis of the integrated AP dataset. (A) PCA of three original AP datasets before batch-effect correction. (B) PCA of the integrated AP dataset after batch-effect correction. (C) The volcano plot representing AP DEGs in the integrated AP dataset. The upregulated genes are presented in red dots, whereas, the downregulated genes are presented in blue dots. (D) Heatmap plot of DEGs (up- and downregulated genes each displaying the top 10)