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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Correlation between large rearrangements and patient phenotypes in NF1 deletion syndrome: an update and review

Fig. 1

Illustration of the genomic region harboring the NF1 and adjacent genes. Red, green, and blue intervals represent the deletion extent in the recurrently observed type-1, type-2, and type-3 NF1 deletions respectively. NF1 is depicted in orange; SUZ12 and its pseudogene SUZ12P1 in green. Purple intervals indicate low-copy repeats (LCRs) implicated in non-allelic homologous recombination (NAHR) at the origin of type-1 and type-3 deletions. Arrows adjacent to gene symbols denote transcriptional orientation. Cen and tel refer to centromeric and telomeric direction, respectively

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BMC Medical Genomics

ISSN: 1755-8794

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