Table 3 The interaction between GRS with CSI and N6/N3 on metabolic syndrome risk factors in obese and overweight women (n = 279)

Anthropometric measurements

WC (cm)

T1

Reference

Reference

Reference

T2

1.67

-5.48, 8.84

0.646

1.60

-5.37, 8.59

0.652

-1.17

-8.66, 6.31

0.758

-0.56

-7.83, 6.70

0.879

T3

-3.56

-10.41, 3.28

0.307

-4.20

-10.87, 2.46

0.216

-3.44

-10.11, 3.21

0.310

-3.66

-10.16, 2.83

0.269

BF (%)

T1

Reference

Reference

Reference

T2

0.54

-3.69, 4.77

0.802

0.77

-3.42, 4.97

0.718

-2.40

-6.83, 2.02

0.287

-1.58

-5.96, 2.78

0.477

T3

-0.05

-4.10, 3.99

0.978

0.22

-3.78, 4.22

0.913

2.78

-1.16, 6.72

0.167

3.55

-0.35, 7.45

0.075

Blood pressure

SBP (mmHg)

T1

Reference

Reference

Reference

T2

2.80

-8.47, 14.08

0.626

2.11

-8.60, 12.82

0.699

8.76

-3.00, 20.53

0.144

7.00

-4.11, 18.11

0.217

T3

1.69

-9.16, 12.54

0.760

0.01

-10.29, 10.33

0.997

-2.47

-12.95, 8.00

0.644

-5.44

-15.38, 4.48

0.283

DBP (mmHg)

T1

Reference

Reference

Reference

T2

5.41

-2.63, 13.47

0.188

5.46

-2.29, 13.22

0.167

2.67

-5.72, 11.08

0.532

1.15

-6.89, 9.20

0.778

T3

3.09

-4.65, 10.85

0.434

2.50

-4.96, 9.97

0.511

-1.89

-9.38, 5.59

0.620

-3.72

-10.91, 3.47

0.311

Metabolic factors

FBS (mg/dl)

T1

Reference

Reference

Reference

T2

0.37

-7.45, 8.20

0.926

-0.07

-7.58, 7.43

0.984

2.78

-5.40, 10.96

0.505

1.45

-6.35, 9.25

0.715

T3

3.02

-4.46, 10.50

0.429

2.81

-4.35, 9.98

0.441

7.21

-0.02, 14.46

0.051

5.54

-1.39, 12.47

0.117

TG (mg/dl)

T1

Reference

Reference

Reference

T2

-14.93

30.23, -74.19

0.621

-16.32

-73.98, 41.34

0.579

14.49

-47.44, 76.43

0.646

10.54

-49.39, 70.48

0.730

T3

25.23

28.91, -31.43

0.383

22.15

-32.92, 77.23

0.431

39.92

-14.88, 94.73

0.153

31.13

-22.11, 84.38

0.252

HDL (mg/dl)

T1

Reference

Reference

Reference

T2

3.18

-5.36, 11.74

0.465

3.38

-5.25, 12.02

0.443

-8.74

-17.68, 0.19

0.055

-8.35

-17.34, 0.62

0.068

T3

2.30

-5.87, 10.48

0.580

2.20

-6.05, 10.45

0.601

-1.56

-9.47, 6.34

0.699

-1.15

-9.13, 6.82

0.777

Variable

GRS

N6/N3

T1

T2

T3

Crude

Model 1

Crude

Model 1

B

CI

P

B

CI

P

B

CI

P

B

CI

P

Anthropometric measurements

WC (cm)

T1

Reference

Reference

Reference

T2

8.45

1.33, 15.57

0.020

7.95

0.83, 15.08

0.029

2.15

-5.39, 9.69

0.576

1.28

-6.29, 8.86

0.740

T3

1.29

-5.07, 7.66

0.690

1.89

-4.46, 8.25

0.559

0.44

-5.91, 6.79

0.892

0.04

-6.28, 6.37

0.989

BF (%)

T1

Reference

T2

3.34

-0.89, 7.58

0.122

3.49

-0.75, 7.74

0.107

1.26

-3.22, 5.75

0.580

1.69

-2.83, 6.21

0.464

T3

0.88

-2.90, 4.67

0.648

0.76

-3.03, 4.55

0.695

2.25

-1.52, 6.03

0.242

2.42

-1.35, 6.19

0.208

Blood pressure

SBP (mmHg)

T1

Reference

Reference

Reference

T2

4.34

-6.45, 15.13

0.431

1.67

-8.78, 12.14

0.754

4.18

-7.28, 15.64

0.475

0.53

-10.53, 11.60

0.925

T3

0.75

− 0.9.06, 10.57

0.881

1.84

-7.59, 11.28

0.702

-5.31

-15.10, 4.46

0.287

-6.69

-16.06, 2.67

0.161

DBP (mmHg)

T1

Reference

T2

4.31

-3.30, 11.93

0.267

3.40

-4.02, 10.82

0.369

1.61

-6.47, 9.70

0.696

-0.56

-8.41, 7.29

0.888

T3

5.28

-1.64, 12.21

0.135

5.93

-0.76, 12.63

0.083

0.73

-6.16, 7.64

0.834

-0.01

-6.66, 6.62

0.995

Metabolic factors

FBS (mg/dl)

T1

Reference

Reference

Reference

T2

2.75

-5.30, 10.81

0.503

0.48

-7.18, 8.16

0.901

3.71

-4.72, 12.14

0.389

1.34

-6.61, 9.30

0.740

T3

5.54

-1.94, 13.03

0.147

6.47

-0.59, 13.53

0.073

5.15

-1.99, 12.30

0.158

3.80

-2.92, 10.52

0.268

TG (mg/dl)

T1

Reference

Reference

Reference

T2

10.52

-50.88, 71.93

0.737

-4.88

-64.99, 55.21

0.873

29.26

-34.98, 93.51

0.372

13.21

-49.11, 75.54

0.678

T3

14.69

-42.37, 71.76

0.614

22.86

-32.48, 78.20

0.418

62.00

7.52, 116.48

0.026

54.42

1.76, 107.08

0.043

HDL (mg/dl)

T1

Reference

Reference

Reference

T2

-3.42

-12.31, 5.47

0.451

-3.25

-12.29, 5.78

0.481

-7.10

-16.41, 2.20

0.135

-6.85

-16.23, 2.51

0.152

T3

-1.55

-9.81, 6.71

0.713

-1.49

-9.82, 6.82

0.725

-2.73

-10.63, 5.15

0.497

-2.42

-10.34, 5.50

0.549